BIOINFORMATICS POSTDOC IN FUNCTIONAL EVOLUTIONARY GENOMICS
Center for Molecular Biology of the University of Heidelberg (ZMBH),
Heidelberg, Germany
A postdoctoral position (2 years with possible extensions) is available
immediately in the evolutionary genomics group of Henrik Kaessmann.
We are seeking highly qualified and enthusiastic applicants with strong
skills in computational biology/bioinformatics, preferably also with
experience in data mining and comparative or evolutionary genome analyses.
We have been interested in a range of topics related to the functional
evolution of genomes across mammals. In the framework of our research, we
are generating comprehensive sets of RNA-seq data for a large collection
of germline and somatic tissues from representatives of all major
mammalian lineages (placental mammals, marsupials, and the egg-laying
monotremes) and evolutionary outgroups (e.g., birds). In conjunction
with various high-throughput genomic and epigenomic datasets, we are
using these transcriptome data to study the functional (expression)
evolution of mammalian genomes across gene types, lineages, tissues,
developmental stages, chromosomes and sexes.
The postdoctoral fellow will perform integrated
evolutionary/bioinformatics analyses based on data produced in our lab and
available genomic data. The specific project will be developed together
with the candidate.
The language of the institute is English, and its members form a highly
international group. The ZMBH is located in Heidelberg, a beautiful
international city next to the Odenwald forest and Neckar river.
For more information on the group and our institute
more generally, please refer to our website at the ZMBH
(http://www.zmbh.uni-heidelberg.de/Kaessmann/) and also our website at the
University of Lausanne (Switzerland, http://www.unil.ch/cig/kaessmann),
where our lab is currently located (before moving to Heidelberg October
1, 2015).
Please submit a CV, statement of research interest, and names of three
references to: Henrik Kaessmann (
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Henrik Kaessmann, Ph.D.
Full Professor
ZMBH
Im Neuenheimer Feld 282
69120 Heidelberg, Germany
Selected recent publications:
Cortez, D., Marin, R., Toledo-Flores, D., Froidevaux, L., Liechti,
A., Waters, P.D., Gr�tzner, F., and Kaessmann, H. (2014) Origins and
functional evolution of Y chromosomes across mammals. Nature 508: 488-493.
Necsulea, A., Soumillon, M., Warnefors, M., Liechti, A., Daish, T.,
Zeller, U., Baker, J.C., Gr�tzner, F., and Kaessmann, H. (2014)
The evolution of lncRNA repertoires and expression patterns in
tetrapods. Nature 505: 635-640.
Necsulea, A. and Kaessmann, H. (2014) Evolutionary dynamics of coding
and noncoding transcriptomes. Nat. Rev. Genet. 5: 734-48.
Meunier, J., Lemoine, F., Soumillon, M., Liechti, A., Weier, M.,
Guschanski, K., Hu, H., Khaitovich, P., and Kaessmann, H. (2013) Birth and
expression evolution of mammalian microRNA genes. Genome Res. 23: 34-45.
Julien, P., Brawand, D., Soumillon, M., Necsulea, A., Liechti, A., Sch�tz,
F., Daish, T., Gr�tzner, F., and Kaessmann, H. (2012) Mechanisms and
evolutionary patterns of mammalian and avian dosage compensation PLoS
Biol. 5:e1001328.
Brawand, D., Soumillon, M., Necsulea, A., Julien, P., Cs�rdi, G.,
Harrigan, P., Weier, M., Liechti, A., Aximu-Petri, A., Kircher, M.,
Albert, F.W., Zeller, U., Khaitovich, P., Gr�tzner, F., Bergmann, S.,
Nielsen, R., P��bo, S., and Kaessmann, H. (2011) The evolution of gene
expression levels in mammalian organs. Nature 478: 343-348. |
