Post Doctoral Research Associate in host-pathogen evolutionary ecology
Vacancy Ref: : 031106
Closing Date : 22-Sep-2014
The Vale Lab at the University of Edinburgh is looking to recruit a
Post-doctoral Research Associate (PDRA).
The Vale lab is closely
affiliated with the Centre for Immunity, Infection and Evolution
(http://ciie.bio.ed.ac.uk/) and works on the evolutionary ecology of
infectious disease, focusing on the fruit fly Drosophila as model host
of viral infection. The postdoctoral position will be funded by a
Society in Science [UTF-8?]â Branco Weiss grant to investigate how individual
variation in resistance and tolerance may influence disease spread and
pathogen evolution.
The specific focus of the project is flexible according to the interests
of the successful candidate, but should ideally address the genetic
basis of variation in host tolerance to viral infection, or the
consequences of this variation for disease transmission and viral
evolution.
This project will take advantage of the vast resources offered by
Drosophila as a model system for the evolutionary ecology and genetics
of host-pathogen interactions. Specifically, key infection phenotypes
pertaining to resistance and tolerance will be measured on lines derived
from the Drosophila Genetic Reference Panel (DGRP). The fully sequenced
genomes of these lines allow high resolution mapping of phenotypes to
genome-wide SNP data. The emphasis in the lab is to achieve a
multifaceted view of host health, complimenting traditional measures
such as host survival with more subtle but equally important measures of
host morbidity such as fecundity, activity and sleep cycles, feeding
rate, or foraging and courtship behaviours. Depending on the [UTF-8?]candidateâs
interests and skills, there is therefore scope to focus on host
life-history, physiological health, or sickness behaviours under
infection. We therefore welcome applications from candidates with a wide
range of interests.
We are looking for someone who is self-driven and looking to work
independently within a small but dynamic group. Candidates should have
or should shortly obtain a PhD with a strong background in host-pathogen
interactions, evolutionary ecology, evolutionary genetics, or similar
field, with the demonstrated ability to publish in peer-reviewed
journals. The ideal candidate should have previous experience in
designing and executing large experiments with Drosophila, or other
invertebrates. Experience with molecular techniques (RNA extraction,
PCR, qPCR, cell culture) would be particularly advantageous, as these
skills are central to the project.
The position is initially available for 24 months, with the possibility
of extension. The starting date is flexible, but early (Jan/Feb) 2015 is
preferred.
Informal inquiries can be made directly to Dr. Pedro Vale
(
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), but full applications must be made by following
the link to the University of Edinburgh's recruitment website (or
searching the for vacancy Ref 031106):
https://www.vacancies.ed.ac.uk/pls/corehrrecruit/erq_jobspec_version_4.jobspec?p_id=031106
The online system allows you to submit a CV and other attachments.
For further information about our research, please see:
http://pedrovale.bio.ed.ac.uk/
We look forward to receiving your application.
--
Pedro F. Vale
Centre for Immunity, Infection and Evolution
School of Biological Sciences, University of Edinburgh
Ashworth Labs, Kings Buildings
West Mains Road
EH9 3JT Edinburgh
Scotland, United Kingdom
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